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Peptide record

TPDB20314

Antibacterial Toxicity modified_plain modified
23 amino acids
Basic Information
3D PDB MODEL
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TPDB20314
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 23-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GLKKIFKAGLGSLVKGIXAHVAS
Physicochemical Analysis
C102H176N28O25
RNDCEQMPTWY
GK
2194.69
11.00
5
0
11
+4
1.42
0.652
123.04
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
1
H
2
I
3
L
4
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 1 I: 2 L: 3 K: 4 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
23
C102H176N28O25
2194.69
11.00
+4
1.42
0.652
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
30 µM
Hemolytic Cytotoxic
50% Hemolysis | 30 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent and rapid bactericidal action of alyteserin-1c and its [E4K] analog against multidrug-resistant strains of Acinetobacter baumannii. | Peptides | 2010