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Peptide record

TPDB20305

Antibacterial Antiparasitic Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB20305
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0 ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from Peptipedia, dbAMP 3.0, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GLKDWWNKHKDKIVKVVKEMGKAGINAAGK
Physicochemical Analysis
C152H250N44O39S1
RCQFPSTY
K
3349.99
10.53
9
3
12
+5
8.83
-0.753
78.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
328.36
2
Residue Composition
number
3
A
0
R
2
N
2
D
0
C
1
E
0
Q
4
G
1
H
2
I
1
L
8
K
1
M
0
F
0
P
0
S
0
T
2
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 2 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 1 K: 8 M: 1 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 3
Chemical Descriptors
30
C152H250N44O39S1
3349.99
10.53
+5
8.83
-0.753
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
16.7±2 µM
Cytotoxic
50% Cell death | 16.7±2 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
The dinoponeratoxin peptides from the giant ant Dinoponera quadriceps display in vitro antitrypanosomal activity. | Biol Chem | 2018