Back to search

Peptide record

TPDB20280

Antibacterial Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20280
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
GLFGVLGSIAKHLLPHVVPVIAEKL
Physicochemical Analysis
C125H207N31O29
RNDCQMTWY
L
2608.21
9.88
4
1
14
+1
2.37
1.132
163.60
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
3
G
2
H
2
I
5
L
2
K
0
M
1
F
2
P
1
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 2 I: 2 L: 5 K: 2 M: 0 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
25
C125H207N31O29
2608.21
9.88
+1
2.37
1.132
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
17.5 µM
Cytotoxic
50% Cell death | 17.5 | µM | target cell: CD4+ T Lymphocytes

Target

CD4+ T Lymphocytes

Source & Reference

NA
DBAASP
Inhibition of HIV Infection by Caerin 1 Antimicrobial Peptides | Peptides | 2015
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.26026377]CD4+ T Lymphocytes:50% cell death at 17.5 µM.

Source & Reference

NA
DRAMP
Peptides. 2015 Sep 71:296-303. ##Antibiotics (Basel). 2020 Sep 30 9(10):661.