Back to search

Peptide record

TPDB20275

Antibacterial Antifungal Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20275
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
GLFDVIKKVASVIGPLGIAGQGGD
Physicochemical Analysis
C105H175N27O31
RNCEHMTWY
G
2311.71
6.87
2
2
11
-0
2.35
0.708
125.83
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
2
D
0
C
0
E
1
Q
6
G
0
H
3
I
2
L
2
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 6 H: 0 I: 3 L: 2 K: 2 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
24
C105H175N27O31
2311.71
6.87
-0
2.35
0.708
Evidence Records 4 records
Evidence 1 Activity

Activity

9.6% Hemolysis
Toxicity
90 µM
Hemolytic Cytotoxic
9.6% Hemolysis | 90 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The design and anticancer activity of a citropin1.1 hybrid peptide with selective activity against highly invasive metastatic cell lines. | Int J Res Pharm Sci | 2019
Evidence 2 Activity

Activity

6.3% Hemolysis
Toxicity
70 µM
Hemolytic Cytotoxic
6.3% Hemolysis | 70 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The design and anticancer activity of a citropin1.1 hybrid peptide with selective activity against highly invasive metastatic cell lines. | Int J Res Pharm Sci | 2019
Evidence 3 Activity

Activity

3.8% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
3.8% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The design and anticancer activity of a citropin1.1 hybrid peptide with selective activity against highly invasive metastatic cell lines. | Int J Res Pharm Sci | 2019
Evidence 4 Activity

Activity

1.9% Hemolysis
Toxicity
30 µM
Hemolytic Cytotoxic
1.9% Hemolysis | 30 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The design and anticancer activity of a citropin1.1 hybrid peptide with selective activity against highly invasive metastatic cell lines. | Int J Res Pharm Sci | 2019