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Peptide record

TPDB20252

Antibacterial Antifungal Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB20252
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
GLEEELQFSLGSKINVK
Physicochemical Analysis
C84H139N21O28
ARDCHMPTWY
EL
1891.15
4.55
2
3
6
-1
6.27
-0.282
108.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
3
E
1
Q
2
G
0
H
1
I
3
L
2
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 3 Q: 1 G: 2 H: 0 I: 1 L: 3 K: 2 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C84H139N21O28
1891.15
4.55
-1
6.27
-0.282
Evidence Records 4 records
Evidence 1 Activity

Activity

<10% Cell death
Toxicity
100 µg/mL
Cytotoxic
<10% Cell death | 100 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Antiviral Activity of Synthetic Peptides Derived from Physiological Proteins. | Intervirology | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
A Peptide Found in Human Serum, Derived from the C-Terminus of Albumin, Shows Antifungal Activity In Vitro and In Vivo. | Microorganisms | 2020
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Peptide Found in Human Serum, Derived from the C-Terminus of Albumin, Shows Antifungal Activity In Vitro and In Vivo. | Microorganisms | 2020
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.30654366]<10% cytotoxicity against Vero cells at the concentration of 100µg/ mL.

Source & Reference

NA
DRAMP
Intervirology. 2018 61(4):166-173.