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Peptide record

TPDB20234

Antibacterial Toxicity modified_plain modified
27 amino acids
Basic Information
3D PDB MODEL
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TPDB20234
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 27-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GKGLXXFKXXKFXXFKXXKFXXFKFKR
Physicochemical Analysis
C112H169N27O18
ANDCEQHIMPSTWYV
K
2181.74
11.93
8
0
7
+8
0.42
-0.444
14.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
1
L
7
K
0
M
6
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 7 M: 0 F: 6 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
27
C112H169N27O18
2181.74
11.93
+8
0.42
-0.444
Evidence Records 1 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
100% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De novo design of selective antibiotic peptides by incorporation of unnatural amino acids. | J Med Chem | 2007