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Peptide record

TPDB20228

Antibacterial standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB20228
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 20-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GKPNKPRPAPIKPRPPHPRL
Physicochemical Analysis
C103H173N35O22
DCEQMFSTWYV
P
2253.73
12.71
7
0
3
+6
9.35
-1.750
44.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
3
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
1
L
3
K
0
M
0
F
8
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 1 K: 3 M: 0 F: 0 P: 8 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C103H173N35O22
2253.73
12.71
+6
9.35
-1.750
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.25 µM

Target

Escherichia coli BL21

Source & Reference

NA

Other

active against E. coli BL21 (MIC 0.25 uM) and K. pneumoniae AR-0112 (MIC 2-8 uM) in 33% TSB and RPMI/serum. Warning: nonstandard as
Evidence 2 Activity

Activity

MIC
Antibacterial
2-8 µM

Target

Klebsiella pneumoniae AR-0112

Source & Reference

NA

Other

active against E. coli BL21 (MIC 0.25 uM) and K. pneumoniae AR-0112 (MIC 2-8 uM) in 33% TSB and RPMI/serum. Warning: nonstandard assays. other bacteria not tested.