Back to search

Peptide record

TPDB20227

Antibacterial Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20227
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GKLWLKG
Physicochemical Analysis
C39H64N10O8
ARNDCEQHIMFPSTYV
GLK
801.00
10.60
2
0
3
+2
-0.97
-0.271
111.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
686.64
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
2
L
2
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 2 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C39H64N10O8
801.00
10.60
+2
-0.97
-0.271
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>128 µM
Hemolytic Cytotoxic
5% Hemolysis | >128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric ?-helical peptides with Gly-Gly pairs. | Sci Rep | 2015