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Peptide record

TPDB20217

Antibacterial Antifungal Antiviral Toxicity modified_plain modified
19 amino acids
Basic Information
3D PDB MODEL
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TPDB20217
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP dbAMP 3.0
modified_plain
Yes
A 19-aa modified multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Modified, details unspecified
Sequence
GKPRPYXPRPXSHPRPIRV
Physicochemical Analysis
C91H148N32O20
ANDCEQLMFTW
P
2010.38
12.41
6
0
3
+5
6.85
-1.500
35.79
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
74.12
2
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
0
L
1
K
0
M
0
F
6
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 0 K: 1 M: 0 F: 0 P: 6 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
19
C91H148N32O20
2010.38
12.41
+5
6.85
-1.500
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>45.5 µM
Cytotoxic
50% Cell death | >45.5 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010