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Peptide record

TPDB20184

Antibacterial Anticancer Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB20184
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Sequence
GKKPGWWKAK
Physicochemical Analysis
C58H88N16O11
RNDCEQHILMFSTYV
K
1185.44
11.00
4
0
3
+4
0.56
-1.800
10.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
927.93
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
4
K
0
M
0
F
1
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
10
C58H88N16O11
1185.44
11.00
+4
0.56
-1.800
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Antimicrobial Activity of Small Synthetic Peptides Based on the Marine Peptide Turgencin A: Prediction of Antimicrobial Peptide Sequences in a Natural Peptide and Strategy for Optimization of Potency. | Int J Mol Sci | 2020
Evidence 2 Activity

Activity

<1% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
<1% Hemolysis | 250 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity of Small Synthetic Peptides Based on the Marine Peptide Turgencin A: Prediction of Antimicrobial Peptide Sequences in a Natural Peptide and Strategy for Optimization of Potency. | Int J Mol Sci | 2020