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Peptide record

TPDB20181

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB20181
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Sequence
GKKGGKGGKGKGK
Physicochemical Analysis
C50H95N19O14
ARNDCEQHILMFPSTWYV
G
1186.42
11.21
6
0
0
+6
6.01
-2.015
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
7
G
0
H
0
I
0
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 7 H: 0 I: 0 L: 0 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C50H95N19O14
1186.42
11.21
+6
6.01
-2.015
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>32 µg/mL
Cytotoxic
50% Cytotoxicity | >32 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives. | Sci Rep | 2019