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Peptide record

TPDB20173

Antibacterial Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB20173
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIVKXIVKXIVKXI
Physicochemical Analysis
C59H112N14O12
ARNDCEQHLMFPSTWY
I
1209.62
10.84
3
0
7
+3
1.95
1.321
173.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
4
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 4 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
14
C59H112N14O12
1209.62
10.84
+3
1.95
1.321
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
4000 µM
Hemolytic Cytotoxic
50% Hemolysis | 4000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hydrophobic Control of the Bioactivity and Cytotoxicity of de Novo-Designed Antimicrobial Peptides. | ACS Appl Mater Interfaces | 2019