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Peptide record

TPDB20163

Antibacterial Antifungal Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB20163
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GIWKKWIKKWLKVLKNLF
Physicochemical Analysis
C119H186N28O20
ARDCEQHMPSTY
K
2328.96
11.21
6
0
10
+6
-2.54
-0.144
124.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
708.47
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
3
L
6
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 3 K: 6 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
18
C119H186N28O20
2328.96
11.21
+6
-2.54
-0.144
Evidence Records 5 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
5.65±0.85 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 5.65±0.85 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
55.2±11.9 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 55.2±11.9 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 3 Activity

Activity

IC50
Toxicity
4.43±0.39 µg/mL
Cytotoxic
IC50 | 4.43±0.39 | µg/mL | target cell: Human vaginal epithelial cells VK2/E6E7

Target

Human vaginal epithelial cells VK2/E6E7

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 4 Activity

Activity

IC50
Toxicity
4.33±0.52 µg/mL
Cytotoxic
IC50 | 4.33±0.52 | µg/mL | target cell: Human esophagus epithelial cells Het-1A

Target

Human esophagus epithelial cells Het-1A

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis