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Peptide record

TPDB20162

Antibacterial Antifungal Hemolysis Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB20162
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GIWKKWIKKWLKKLKNLF
Physicochemical Analysis
C120H189N29O20
ARDCEQHMPSTYV
K
2358.00
11.29
7
0
9
+7
-1.62
-0.594
108.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
699.74
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
3
L
7
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 3 K: 7 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
18
C120H189N29O20
2358.00
11.29
+7
-1.62
-0.594
Evidence Records 5 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
49.38±5.14 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 49.38±5.14 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 3 Activity

Activity

IC50
Toxicity
8.75±1.04 µg/mL
Cytotoxic
IC50 | 8.75±1.04 | µg/mL | target cell: Human vaginal epithelial cells VK2/E6E7

Target

Human vaginal epithelial cells VK2/E6E7

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 4 Activity

Activity

IC50
Toxicity
9.75±1.34 µg/mL
Cytotoxic
IC50 | 9.75±1.34 | µg/mL | target cell: Human esophagus epithelial cells Het-1A

Target

Human esophagus epithelial cells Het-1A

Source & Reference

NA
DBAASP
Activity of Novel Synthetic Peptides against Candida albicans. | Sci Rep | 2015
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis