Back to search

Peptide record

TPDB20140

Antibacterial Anticancer Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20140
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0 ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, CancerPPD 2.0, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GIPCGESCVFIPCLTSAIGCSCKSKVCYRN
Physicochemical Analysis
C132H216N36O40S6
DQHMW
C
3139.74
8.02
3
1
9
+2
1.79
0.547
74.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
59.40
13
Residue Composition
number
1
A
1
R
1
N
0
D
6
C
1
E
0
Q
3
G
0
H
3
I
1
L
2
K
0
M
1
F
2
P
4
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 3 L: 1 K: 2 M: 0 F: 1 P: 2 S: 4 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
30
C132H216N36O40S6
3139.74
8.02
+2
1.79
0.547
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
3.19±0.01 µM
Cytotoxic
IC50 | 3.19±0.01 | µM | target cell: Human foreskin fibroblasts (HFF)

Target

Human foreskin fibroblasts (HFF)

Source & Reference

NA
DBAASP
Isolation and characterization of cytotoxic cyclotides from Viola philippica. | Peptides | 2011
Evidence 2 Activity

Activity

IC50
Toxicity
3.19
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: HFF-1: IC50=3.19±0.01µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2011 Aug 32(8):1719-23.