Peptide record

TPDB20135

Vibi E Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB20135
Vibi E
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF Antifungipept ToxinPred 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, ACP740 _ACP240, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
GIPCAESCVWIPCTVTALIGCGCSNKVCYN
Physicochemical Analysis
C132H210N34O40S6
RDQHMF
C
3105.68
5.90
1
1
11
-0
-0.53
0.817
87.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
237.15
13
Residue Composition
number
2
A
0
R
2
N
0
D
6
C
1
E
0
Q
3
G
0
H
3
I
1
L
1
K
0
M
0
F
2
P
2
S
2
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 3 L: 1 K: 1 M: 0 F: 0 P: 2 S: 2 T: 2 W: 1 Y: 1 V: 3
Chemical Descriptors
30
C132H210N34O40S6
3105.68
5.90
-0
-0.53
0.817
Free
L
Not Available
Free
Anticancer
Alpine violetViola biflora
Evidence Records 2 records
Evidence 1 Activity

Activity

Not Available
Anticancer

Target

Leukemia Cancer
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2008

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
Toxicity
3.2 µM
Cytotoxic
Cytotoxicity: [Ref.18191970] Cytotoxicity: Human lymphoma cell line U-937 GTB (IC50=3.2 µM).

Source & Reference

NA
DRAMP
Phytochemistry. 2008 Feb 69(4):939-952.