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Peptide record

TPDB20134

Antibacterial Anticancer Toxicity modified_plain modified
31 amino acids
Basic Information
3D PDB MODEL
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TPDB20134
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 31-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIPCAESCVWIPCTITALXGCSCKNNVCYNN
Physicochemical Analysis
C133H210N36O42S6
RDQHMF
C
3177.71
5.90
1
1
10
-0
0.23
0.442
75.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
231.77
15
Residue Composition
number
2
A
0
R
4
N
0
D
6
C
1
E
0
Q
2
G
0
H
3
I
1
L
1
K
0
M
0
F
2
P
2
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 4 D: 0 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 3 L: 1 K: 1 M: 0 F: 0 P: 2 S: 2 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
31
C133H210N36O42S6
3177.71
5.90
-0
0.23
0.442
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>25 µM
Hemolytic Cytotoxic
50% Hemolysis | >25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities. | J Biol Chem | 2012
Evidence 2 Activity

Activity

HD50
Toxicity
25 µM
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: HD50>25 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 2012 May 18 287(21):17598-17607.