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Peptide record

TPDB20123

Antibacterial Toxicity modified_plain modified
23 amino acids
Basic Information
3D PDB MODEL
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TPDB20123
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 23-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIGXFLHSAXXFGXAFVGEIMNS
Physicochemical Analysis
C90H132N22O25S1
RDCQKPTWY
G
1954.23
5.13
1
1
10
-1
-1.37
0.761
72.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
1
H
2
I
1
L
0
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 1 K: 0 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C90H132N22O25S1
1954.23
5.13
-1
-1.37
0.761
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
721.1±65.3 µM
Hemolytic Cytotoxic
50% Hemolysis | 721.1±65.3 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity. | PLoS One | 2016
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>1000 µM
Hemolytic Cytotoxic
50% Hemolysis | >1000 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity. | PLoS One | 2016