Peptide record

TPDB20109

Antibacterial Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB20109
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 29-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GILDTLKQLGKAAVQGLLSKAACKLAKTC
Physicochemical Analysis
C129H232N36O37S2
RNEHMFPWY
L
2943.60
10.06
5
1
13
+4
2.85
0.417
121.38
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.25
7
Residue Composition
number
5
A
0
R
0
N
1
D
2
C
0
E
2
Q
3
G
0
H
1
I
6
L
5
K
0
M
0
F
0
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 1 C: 2 E: 0 Q: 2 G: 3 H: 0 I: 1 L: 6 K: 5 M: 0 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
29
C129H232N36O37S2
2943.60
10.06
+4
2.85
0.417
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2-4 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 2-4 ug/ml), S. enteritidis (MIC 16-32 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
16-32 µg/mL

Target

S. enteritidis

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 2-4 ug/ml), S. enteritidis (MIC 16-32 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 2-4 ug/ml), S. enteritidis (MIC 16-32 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml).
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP