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Peptide record

TPDB20099

Antibacterial Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB20099
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, PD_Hemolysis, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GIKSALLGIAKNVGMSLLQKAQCKLSGSC
Physicochemical Analysis
C125H224N36O37S3
RDEHFPTWY
L
2919.55
10.17
4
0
12
+4
1.53
0.469
114.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.28
9
Residue Composition
number
3
A
0
R
1
N
0
D
2
C
0
E
2
Q
4
G
0
H
2
I
5
L
4
K
1
M
0
F
0
P
4
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 2 G: 4 H: 0 I: 2 L: 5 K: 4 M: 1 F: 0 P: 0 S: 4 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
29
C125H224N36O37S3
2919.55
10.17
+4
1.53
0.469
Evidence Records 5 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
49.04 µM
Hemolytic Cytotoxic
50% Hemolysis | 49.04 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Functional characterization of two novel peptides and their analogs identifed from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India | Chemoecology | 2019
Evidence 2 Activity

Activity

LD50
Toxicity
52.71 µM
Cytotoxic
LD50 | 52.71 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Functional characterization of two novel peptides and their analogs identifed from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India | Chemoecology | 2019
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
24.53 µM
Hemolytic Cytotoxic
50% Hemolysis | 24.53 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Functional characterization of two novel peptides and their analogs identifed from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India | Chemoecology | 2019
Evidence 4 Activity

Activity

LD50
Toxicity
30.54 µM
Cytotoxic
LD50 | 30.54 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Functional characterization of two novel peptides and their analogs identifed from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India | Chemoecology | 2019
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis