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Peptide record

TPDB20087

Antibacterial Toxicity modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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TPDB20087
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 17-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIKKFLKXAKKXVKAFK
Physicochemical Analysis
C85H148N22O16
RNDCEQHMPSTWY
K
1734.25
11.29
7
0
7
+7
3.54
-0.353
74.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
7
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 7 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C85H148N22O16
1734.25
11.29
+7
3.54
-0.353
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
3.125 µM
Hemolytic Cytotoxic
50% Hemolysis | 3.125 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of Antimicrobial Stapled Peptides Based on Magainin 2 Sequence. | Molecules | 2021