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Peptide record

TPDB20080

Antibacterial Anticancer Toxicity modified_plain modified
35 amino acids
Basic Information
3D PDB MODEL
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TPDB20080
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 35-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIKEXLCNXACAQTVCKKSGGPLCDTCQAACKALG
Physicochemical Analysis
C133H230N40O44S6
RHMFWY
C
3285.89
8.02
4
2
10
+2
5.48
0.160
67.14
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
375
11.41
12
Residue Composition
number
5
A
0
R
1
N
1
D
6
C
1
E
2
Q
4
G
0
H
1
I
3
L
4
K
0
M
0
F
1
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 1 C: 6 E: 1 Q: 2 G: 4 H: 0 I: 1 L: 3 K: 4 M: 0 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
35
C133H230N40O44S6
3285.89
8.02
+2
5.48
0.160
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
>50.0 µM
Cytotoxic
IC50 | >50.0 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Isolation and Characterization of Antimicrobial Peptides With Unusual Disulfide Connectivity From the Colonial Ascidian Synoicum turgens | Mar Drugs | 2020
Evidence 2 Activity

Activity

IC50
Toxicity
50 µM
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: MRC-5: IC50> 50 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Mar Drugs. 2020 Jan 12 18(1):51.