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Peptide record

TPDB20074

Antibacterial Antifungal Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB20074
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GIKEFAHSLGKFGKAFFGGILNQ
Physicochemical Analysis
C117H176N30O29
RDCMPTWYV
G
2466.87
10.32
4
1
10
+2
0.53
0.139
76.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
1
Q
5
G
1
H
2
I
2
L
3
K
0
M
4
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 5 H: 1 I: 2 L: 2 K: 3 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C117H176N30O29
2466.87
10.32
+2
0.53
0.139
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µM

Target

Candida albicans NCTC 3179

Source & Reference

NA

Other

n 2014 using more bacteria revealed selective activity against certain strains, including C. albicans NCTC 3179 (MIC 100 uM), Gram+ S. mutans ATCC 10449 (MIC 50 uM), Gram- F. nucleatum NCTC 10562 (MIC 12.5 uM). The
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µM

Target

S. mutans ATCC 10449

Source & Reference

NA

Other

ive activity against certain strains, including C. albicans NCTC 3179 (MIC 100 uM), Gram+ S. mutans ATCC 10449 (MIC 50 uM), Gram- F. nucleatum NCTC 10562 (MIC 12.5 uM). These are mostly oral bacteria. It also bin
Evidence 3 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

F. nucleatum NCTC 10562

Source & Reference

NA

Other

cluding C. albicans NCTC 3179 (MIC 100 uM), Gram+ S. mutans ATCC 10449 (MIC 50 uM), Gram- F. nucleatum NCTC 10562 (MIC 12.5 uM). These are mostly oral bacteria. It also binds LPS ( McLean et al., 2014 ).
Evidence 4 Activity

Activity

MIC
Antifungal
100 µM

Target

Candida albicans NCTC 3179

Source & Reference

CAFPdb Antifungipept

Other

n 2014 using more bacteria revealed selective activity against certain strains, including C. albicans NCTC 3179 (MIC 100 uM), Gram+ S. mutans ATCC 10449 (MIC 50 uM), Gram- F. nucleatum NCTC 10562 (MIC 12.5 uM). The
Evidence 5 Activity

Activity

MIC
Antifungal
50 µM

Target

S. mutans ATCC 10449

Source & Reference

CAFPdb Antifungipept

Other

ive activity against certain strains, including C. albicans NCTC 3179 (MIC 100 uM), Gram+ S. mutans ATCC 10449 (MIC 50 uM), Gram- F. nucleatum NCTC 10562 (MIC 12.5 uM). These are mostly oral bacteria. It also bin
Evidence 6 Activity

Activity

MIC
Antifungal
12.5 µM

Target

F. nucleatum NCTC 10562

Source & Reference

CAFPdb Antifungipept

Other

cluding C. albicans NCTC 3179 (MIC 100 uM), Gram+ S. mutans ATCC 10449 (MIC 50 uM), Gram- F. nucleatum NCTC 10562 (MIC 12.5 uM). These are mostly oral bacteria. It also binds LPS ( McLean et al., 2014 ).