Back to search

Peptide record

TPDB20068

Antibacterial Antifungal Toxicity modified_plain modified
45 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20068
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 45-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
GIINTLQKYYXRVRGGRXAVLSXLPKEEQIGKXSTRGRKXXRRKK
Physicochemical Analysis
C198H347N69O53
DCHMFW
R
4542.36
12.06
13
2
11
+11
13.75
-1.033
67.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
2980
65.60
9
Residue Composition
number
1
A
7
R
1
N
0
D
0
C
2
E
2
Q
5
G
0
H
3
I
3
L
6
K
0
M
0
F
1
P
2
S
2
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 7 N: 1 D: 0 C: 0 E: 2 Q: 2 G: 5 H: 0 I: 3 L: 3 K: 6 M: 0 F: 0 P: 1 S: 2 T: 2 W: 0 Y: 2 V: 2
Chemical Descriptors
45
C198H347N69O53
4542.36
12.06
+11
13.75
-1.033
Evidence Records 1 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Linear analogues of human beta-defensin 3: concepts for design of antimicrobial peptides with reduced cytotoxicity to mammalian cells. | Chembiochem | 2008