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Peptide record

TPDB20067

Antibacterial standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB20067
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 23-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GIINTLQKYYSRVRGGRSAVLSS
Physicochemical Analysis
C110H185N35O33
DCEHMFPW
S
2525.89
11.35
4
0
9
+4
1.46
-0.230
97.39
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
2980
117.98
9
Residue Composition
number
1
A
3
R
1
N
0
D
0
C
0
E
1
Q
3
G
0
H
2
I
2
L
1
K
0
M
0
F
0
P
4
S
1
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 2 L: 2 K: 1 M: 0 F: 0 P: 0 S: 4 T: 1 W: 0 Y: 2 V: 2
Chemical Descriptors
23
C110H185N35O33
2525.89
11.35
+4
1.46
-0.230
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

LD90 (lethal dose killing > 90%): active against E. coli WBB01 or ATCC 11775 (LD90 0.78-1.56 ug/ml), S. enterica sv Minnesota strain R595 or R60 or PXG1 (L90 0.1-0.39 ug/ml), P. mirabilis R45 (LD90 25 ug/ml), B. cepacia WaaC::kann (LD90 50 ug/ml), B.cepacia ATCC 25416 (LD90 > 100 ug/ml), and P. aeruginosa ATCC 1014 (LD90 0.2 ug/ml). Warning: other bacteria not tested.