Back to search

Peptide record

TPDB20064

Antibacterial Toxicity standard
91 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB20064
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 91-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKKGGGGMGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
Physicochemical Analysis
C417H707N135O113S13
W
G
9836.82
10.07
21
3
22
+17
18.73
-0.389
62.09
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5220
53.07
27
Residue Composition
number
2
A
9
R
1
N
1
D
12
C
2
E
3
Q
15
G
1
H
6
I
5
L
11
K
1
M
1
F
6
P
3
S
5
T
0
W
3
Y
4
V
Amino Acid Distribution
A: 2 R: 9 N: 1 D: 1 C: 12 E: 2 Q: 3 G: 15 H: 1 I: 6 L: 5 K: 11 M: 1 F: 1 P: 6 S: 3 T: 5 W: 0 Y: 3 V: 4
Chemical Descriptors
91
C417H707N135O113S13
9836.82
10.07
+17
18.73
-0.389
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Bacterial expression and antibiotic activities of recombinant variants of human ?-defensins on pathogenic bacteria and M. tuberculosis. | Protein Expr Purif | 2013