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Peptide record

TPDB20055

Antibacterial Anticancer standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB20055
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0 dbACP
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia, CancerPPD 2.0, and dbACP, with an available 3D structural model.
Sequence
GIFKDTLKKVVAAVLTTVADNIHPK
Physicochemical Analysis
C123H208N32O34
RCEQMSWY
KV
2679.20
10.16
5
2
12
+2
5.58
0.328
120.80
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
3
A
0
R
1
N
2
D
0
C
0
E
0
Q
1
G
1
H
2
I
2
L
4
K
0
M
1
F
1
P
0
S
3
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 2 K: 4 M: 0 F: 1 P: 1 S: 0 T: 3 W: 0 Y: 0 V: 4
Chemical Descriptors
25
C123H208N32O34
2679.20
10.16
+2
5.58
0.328
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
62.5 µM

Target

Staphylococcus aureus ATCC 12600

Source & Reference

NA

Other

active against Gram+ S. aureus ATCC 12600 (MIC 62.5 uM), Gram- E. coli ATCC 35218 (MIC 7.8 uM), K. pneumoniae ATCC 49472 (MIC 15.6 uM), and P. ae
Evidence 2 Activity

Activity

MIC
Antibacterial
7.8 µM

Target

Escherichia coli ATCC 35218

Source & Reference

NA

Other

active against Gram+ S. aureus ATCC 12600 (MIC 62.5 uM), Gram- E. coli ATCC 35218 (MIC 7.8 uM), K. pneumoniae ATCC 49472 (MIC 15.6 uM), and P. aeruginosa ATCC 9072 (MIC 15.6 uM). Also
Evidence 3 Activity

Activity

MIC
Antibacterial
15.6 µM

Target

Klebsiella pneumoniae ATCC 49472

Source & Reference

NA

Other

against Gram+ S. aureus ATCC 12600 (MIC 62.5 uM), Gram- E. coli ATCC 35218 (MIC 7.8 uM), K. pneumoniae ATCC 49472 (MIC 15.6 uM), and P. aeruginosa ATCC 9072 (MIC 15.6 uM). Also showed cytotoxicity to cancer cells lung
Evidence 4 Activity

Activity

MIC
Antibacterial
15.6 µM

Target

Pseudomonas aeruginosa ATCC 9072

Source & Reference

NA

Other

5 uM), Gram- E. coli ATCC 35218 (MIC 7.8 uM), K. pneumoniae ATCC 49472 (MIC 15.6 uM), and P. aeruginosa ATCC 9072 (MIC 15.6 uM). Also showed cytotoxicity to cancer cells lung adenocarcinoma A549 (IC50 30.7 uM), breast