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Peptide record

TPDB20015

MSI-136 Antibacterial Anticancer standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB20015
MSI-136
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP dbAMP 3.0 iACP-DRLF
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia, ACP740 _ACP240, AntiCP 2.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
GIGKFLKKAKKFAKAFVKIINN-NH2
Physicochemical Analysis
C119H199N31O25
RDCEQHMPSTWY
K
2464.08
11.29
7
0
11
+7
2.47
0.009
97.73
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
0
R
2
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
1
L
7
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 1 K: 7 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C119H199N31O25
2464.08
11.29
+7
2.47
0.009
Amidation
L
Linear
Free
Antibacterial
African clawed frog Xenopus laevis skin
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50=10 µM
Anticancer
10 µM

Target

Lung Cancer
A-549
Lung

Assay & Model

MTT/MTS assay
48-h

Source & Reference

dbAMP 3.0 CancerPPD 2.0 dbACP SATPdb
CancerPPD2
1993

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation. dbAMP 3.0 classified as Anticancer under the disease-associated peptide function classes.