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Peptide record

TPDB20006

Antibacterial Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB20006
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GIGKFLHSGGKNLKALAALAKKIL
Physicochemical Analysis
C114H198N32O27
RDCEQMPTWYV
LK
2449.02
11.12
6
0
12
+5
1.27
0.392
130.42
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
0
Q
4
G
1
H
2
I
5
L
5
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 1 I: 2 L: 5 K: 5 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C114H198N32O27
2449.02
11.12
+5
1.27
0.392
Evidence Records 2 records
Evidence 1 Activity

Activity

0.59% Hemolysis
Toxicity
160 µM
Hemolytic Cytotoxic
0.59% Hemolysis | 160 | µM | target cell: Cattle erythrocytes

Target

Cattle erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Antibacterial Activity of Magainin and Mastoparan and Its Novel Hybrid Against MDR E. coli Isolates of Neonatal Calves | Int J Pept Res Ther | 2021
Evidence 2 Activity

Activity

2.22% Hemolysis
Toxicity
160 µM
Hemolytic Cytotoxic
2.22% Hemolysis | 160 | µM | target cell: Dog erythrocytes

Target

Dog erythrocytes

Source & Reference

NA
DBAASP
Evaluation of Antibacterial Activity of Magainin and Mastoparan and Its Novel Hybrid Against MDR E. coli Isolates of Neonatal Calves | Int J Pept Res Ther | 2021