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Peptide record

TPDB19999

Antibacterial Toxicity modified_plain modified
25 amino acids
Basic Information
3D PDB MODEL
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TPDB19999
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 25-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIGKFLHSAKKWGKAFVGEIMNSXC
Physicochemical Analysis
C119H186N32O30S2
RDQPTY
GK
2609.10
10.17
5
1
10
+3
1.63
0.028
66.40
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
210.80
4
Residue Composition
number
2
A
0
R
1
N
0
D
1
C
1
E
0
Q
4
G
1
H
2
I
1
L
4
K
1
M
2
F
0
P
2
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 1 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 1 K: 4 M: 1 F: 2 P: 0 S: 2 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
25
C119H186N32O30S2
2609.10
10.17
+3
1.63
0.028
Evidence Records 3 records
Evidence 1 Activity

Activity

23% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
23% Hemolysis | 100 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Parallel and antiparallel dimers of magainin 2: their interaction with phospholipid membrane and antibacterial activity. | J Pept Sci | 2002
Evidence 2 Activity

Activity

65% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
65% Hemolysis | 100 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Parallel and antiparallel dimers of magainin 2: their interaction with phospholipid membrane and antibacterial activity. | J Pept Sci | 2002
Evidence 3 Activity

Activity

30% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
30% Hemolysis | 100 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Parallel and antiparallel dimers of magainin 2: their interaction with phospholipid membrane and antibacterial activity. | J Pept Sci | 2002