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Peptide record

TPDB19995

Antibacterial Toxicity modified_plain modified
23 amino acids
Basic Information
3D PDB MODEL
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TPDB19995
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 23-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIGKFLHSAKKFXKAFVGEIMNS
Physicochemical Analysis
C112H177N29O28S1
RDCQPTWY
K
2409.87
10.55
5
1
10
+3
2.58
0.100
72.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
0
Q
3
G
1
H
2
I
1
L
4
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 1 I: 2 L: 1 K: 4 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C112H177N29O28S1
2409.87
10.55
+3
2.58
0.100
Evidence Records 2 records
Evidence 1 Activity

Activity

77% Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
77% Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa. | J Pept Sci | 2015
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa. | J Pept Sci | 2015