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Peptide record

TPDB19977

Antibacterial Toxicity modified_plain modified
23 amino acids
Basic Information
3D PDB MODEL
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TPDB19977
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 23-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIGKFLHSAKKFGKAFXGEIMNS
Physicochemical Analysis
C109H171N29O28S1
RDCQPTWYV
GK
2367.79
10.55
5
1
9
+3
2.52
-0.100
59.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
1
H
2
I
1
L
4
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 1 K: 4 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C109H171N29O28S1
2367.79
10.55
+3
2.52
-0.100
Evidence Records 2 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa. | J Pept Sci | 2015
Evidence 2 Activity

Activity

95% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
95% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa. | J Pept Sci | 2015