Peptide record

TPDB19973

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB19973
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GIGKFLHSAKKFGKAFVGQIMNS
Physicochemical Analysis
C114H181N31O28S1
RDCEPTWY
GK
2465.94
11.00
5
0
10
+4
1.15
0.083
72.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
1
Q
4
G
1
H
2
I
1
L
4
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 4 H: 1 I: 2 L: 1 K: 4 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C114H181N31O28S1
2465.94
11.00
+4
1.15
0.083
Evidence Records 2 records
Evidence 1 Activity

Activity

94.4% Killing
Toxicity
100 µM
Cytotoxic
94.4% Killing | 100 | µM | target cell: Chinese hamster ovary cells CHO-K1

Target

Chinese hamster ovary cells CHO-K1

Source & Reference

NA
DBAASP
Action mechanism of PEGylated magainin 2 analogue peptide. | Biochim Biophys Acta | 2007
Evidence 2 Activity

Activity

3.4% Killing
Toxicity
100 µM
Cytotoxic
3.4% Killing | 100 | µM | target cell: Chinese hamster ovary cells CHO-K1

Target

Chinese hamster ovary cells CHO-K1

Source & Reference

NA
DBAASP
Action mechanism of PEGylated magainin 2 analogue peptide. | Biochim Biophys Acta | 2007