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Peptide record

TPDB19971

Antibacterial Anticancer Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB19971
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GIGKFLHSAKKFGKAFV
Physicochemical Analysis
C89H139N23O19
RNDCEQMPTWY
K
1835.23
11.00
5
0
8
+4
0.55
0.218
74.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
1
H
1
I
1
L
4
K
0
M
3
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 1 L: 1 K: 4 M: 0 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C89H139N23O19
1835.23
11.00
+4
0.55
0.218
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of Amphipathic Antimicrobial Peptide Foldamers Based on Magainin 2 Sequence | ChemMedChem | 2019