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Peptide record

TPDB19968

Antibacterial Toxicity modified_plain modified
23 amino acids
Basic Information
3D PDB MODEL
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TPDB19968
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 23-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GIGKFLHAAKKFXKAFVAEIMNS
Physicochemical Analysis
C113H179N29O27S1
RDCQPTWY
AK
2407.90
10.55
5
1
12
+3
2.10
0.309
80.87
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
1
E
0
Q
2
G
1
H
2
I
1
L
4
K
1
M
3
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 1 I: 2 L: 1 K: 4 M: 1 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C113H179N29O27S1
2407.90
10.55
+3
2.10
0.309
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
25 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 25 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. | J Am Chem Soc | 2015
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. | J Am Chem Soc | 2015