Back to search

Peptide record

TPDB19934

Antibacterial Antiparasitic Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB19934
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0 HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from Peptipedia, dbAMP 3.0, HemoPI, and other sources, with an available 3D structural model.
Sequence
GIGAVLTTGLPALISWIKRKRQQ
Physicochemical Analysis
C114H196N34O29
NDCEHMFY
GIL
2507.02
12.42
4
0
10
+4
0.92
0.130
123.04
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
219.38
5
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
3
I
3
L
2
K
0
M
0
F
1
P
1
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 3 L: 3 K: 2 M: 0 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C114H196N34O29
2507.02
12.42
+4
0.92
0.130
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
16.28±0.17 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 16.28±0.17 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 2 Activity

Activity

50% Cell death
Toxicity
43.42±0.86 µg/mL
Cytotoxic
50% Cell death | 43.42±0.86 | µg/mL | target cell: Human dendritic cells

Target

Human dendritic cells

Source & Reference

NA
DBAASP
Leishmanicidal activity of synthetic antimicrobial peptides in an infection model with human dendritic cells. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis