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Peptide record

TPDB19911

Antibacterial Antifungal Toxicity modified_plain modified
47 amino acids
Basic Information
3D PDB MODEL
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TPDB19911
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 47-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
GIFSKLAGKKLKNLLISGLKNVGKEVGLDVVRTGIDIAGCKIKGECX
Physicochemical Analysis
C213H373N59O60S2
QHMPWY
GK
4784.78
10.11
9
4
18
+5
9.97
0.240
120.21
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
2.61
7
Residue Composition
number
2
A
1
R
2
N
2
D
2
C
2
E
0
Q
8
G
0
H
5
I
6
L
8
K
0
M
1
F
0
P
2
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 2 C: 2 E: 2 Q: 0 G: 8 H: 0 I: 5 L: 6 K: 8 M: 0 F: 1 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
47
C213H373N59O60S2
4784.78
10.11
+5
9.97
0.240
Evidence Records 1 records
Evidence 1 Activity

Activity

24% Hemolysis
Toxicity
15 µM
Hemolytic Cytotoxic
24% Hemolysis | 15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Functional characterisation of the 1-18 fragment of esculentin-1b, an antimicrobial peptide from Rana esculenta. | Peptides | 2003