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Peptide record

TPDB19899

Antibacterial standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB19899
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 24-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GHSVDRIPEYFGPPGLPGPVLFYS
Physicochemical Analysis
C124H177N29O33
ANCQKMTW
P
2601.94
5.22
2
2
9
-1
2.14
-0.100
72.92
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
2980
114.53
4
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
1
E
0
Q
4
G
1
H
1
I
2
L
0
K
0
M
2
F
5
P
2
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 1 L: 2 K: 0 M: 0 F: 2 P: 5 S: 2 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
24
C124H177N29O33
2601.94
5.22
-1
2.14
-0.100
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Cloacaenodin showed no activity against E.coli MG1655, B. subtilis 168, S.enterica serovar Newport, K.aerogenes ATCC 13048, E.hormaechei ATCC 700323, and E.kobei BAA260. However, it inhibited (zones of inhibition) multiple Enterobacter genus strains, including E. cloacae ATCC 13047 (liquid MIC 940 nM 7.5 uM agar), E. cloacae UCI102 clinical (MIC 1.0 iM agar), E. mori DSM 26271 (MIC 1.9 uM Agar), E. asburiae DSM 17506 and clincal strains (MIC 1.0-3.8 uM Agar), E. amnigenus ATCC 33072 (MIC 230 and 500 nM, two methods), E. nimipressuralis DSM 18955 (MIC 1.9 uM Agar), E. ludwigii MGH216 (MIC 1.0 uM agar), E. kobei MGH178 (MIC 2.0 uM agar), and E. hormaechei UCI35 (MIC 2 uM agar).