Back to search

Peptide record

TPDB19855

Antibacterial Antifungal Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB19855
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AFP-GFuse ToxinPred 3.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, AFP-GFuse, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GFLDTLKNIGKTVGKVALDVAKNVLT
Physicochemical Analysis
C123H212N32O36
RCEQHMPSWY
LKV
2715.23
10.16
4
2
12
+2
3.97
0.385
127.31
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
2
A
0
R
2
N
2
D
0
C
0
E
0
Q
3
G
0
H
1
I
4
L
4
K
0
M
1
F
0
P
0
S
3
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 2 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 4 K: 4 M: 0 F: 1 P: 0 S: 0 T: 3 W: 0 Y: 0 V: 4
Chemical Descriptors
26
C123H212N32O36
2715.23
10.16
+2
3.97
0.385
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
11.79 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 11.79 uM), Gram+ S. aureus ATCC 29213 (MIC 23.58 uM), and fungus C. albicans ATCC 10231 (MIC 47.16
Evidence 2 Activity

Activity

MIC
Antibacterial
23.58 µM

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 11.79 uM), Gram+ S. aureus ATCC 29213 (MIC 23.58 uM), and fungus C. albicans ATCC 10231 (MIC 47.16 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
47.16 µM

Target

Candida albicans ATCC 10231

Source & Reference

NA

Other

E. coli ATCC 25922 (MIC 11.79 uM), Gram+ S. aureus ATCC 29213 (MIC 23.58 uM), and fungus C. albicans ATCC 10231 (MIC 47.16 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
11.79 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 11.79 uM), Gram+ S. aureus ATCC 29213 (MIC 23.58 uM), and fungus C. albicans ATCC 10231 (MIC 47.16
Evidence 5 Activity

Activity

MIC
Antifungal
23.58 µM

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against Gram- E. coli ATCC 25922 (MIC 11.79 uM), Gram+ S. aureus ATCC 29213 (MIC 23.58 uM), and fungus C. albicans ATCC 10231 (MIC 47.16 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
47.16 µM

Target

Candida albicans ATCC 10231

Source & Reference

NA

Other

E. coli ATCC 25922 (MIC 11.79 uM), Gram+ S. aureus ATCC 29213 (MIC 23.58 uM), and fungus C. albicans ATCC 10231 (MIC 47.16 uM).
Evidence 7 Activity

Activity

22.3% Hemolysis
Toxicity
188.68 µM
Hemolytic Cytotoxic
22.3% Hemolysis | 188.68 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Picturins and Pictuseptins, two novel antimicrobial peptide families from the skin secretions of the Chachi treefrog, Boana picturata. | J Proteomics | 2022
Evidence 8 Activity

Activity

8.3% Hemolysis
Toxicity
94.32 µM
Hemolytic Cytotoxic
8.3% Hemolysis | 94.32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Picturins and Pictuseptins, two novel antimicrobial peptide families from the skin secretions of the Chachi treefrog, Boana picturata. | J Proteomics | 2022