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Peptide record

TPDB19854

Antibacterial Antifungal Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB19854
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
GFLDTLKNIGKTVGGIALNVLT
Physicochemical Analysis
C102H174N26O30
RCEQHMPSWY
GL
2244.66
9.88
2
1
10
+1
0.49
0.691
137.27
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
1
A
0
R
2
N
1
D
0
C
0
E
0
Q
4
G
0
H
2
I
4
L
2
K
0
M
1
F
0
P
0
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 2 L: 4 K: 2 M: 0 F: 1 P: 0 S: 0 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
22
C102H174N26O30
2244.66
9.88
+1
0.49
0.691
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
14.24 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 14.24 uM), Gram+ S. aureus ATCC 29213 (MIC 57.05 uM), and fungus C.albicans ATCC 10231 (MIC 114.1 u
Evidence 2 Activity

Activity

MIC
Antibacterial
57.05 µM

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 14.24 uM), Gram+ S. aureus ATCC 29213 (MIC 57.05 uM), and fungus C.albicans ATCC 10231 (MIC 114.1 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
114.1 µM

Target

C.albicans ATCC 10231

Source & Reference

NA

Other

E. coli ATCC 25922 (MIC 14.24 uM), Gram+ S. aureus ATCC 29213 (MIC 57.05 uM), and fungus C.albicans ATCC 10231 (MIC 114.1 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
14.24 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 14.24 uM), Gram+ S. aureus ATCC 29213 (MIC 57.05 uM), and fungus C.albicans ATCC 10231 (MIC 114.1 u
Evidence 5 Activity

Activity

MIC
Antifungal
57.05 µM

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 14.24 uM), Gram+ S. aureus ATCC 29213 (MIC 57.05 uM), and fungus C.albicans ATCC 10231 (MIC 114.1 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
114.1 µM

Target

C.albicans ATCC 10231

Source & Reference

NA

Other

E. coli ATCC 25922 (MIC 14.24 uM), Gram+ S. aureus ATCC 29213 (MIC 57.05 uM), and fungus C.albicans ATCC 10231 (MIC 114.1 uM).
Evidence 7 Activity

Activity

31.0% Hemolysis
Toxicity
228.20 µM
Hemolytic Cytotoxic
31.0% Hemolysis | 228.20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Picturins and Pictuseptins, two novel antimicrobial peptide families from the skin secretions of the Chachi treefrog, Boana picturata. | J Proteomics | 2022
Evidence 8 Activity

Activity

15% Hemolysis
Toxicity
114.10 µM
Hemolytic Cytotoxic
15% Hemolysis | 114.10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Picturins and Pictuseptins, two novel antimicrobial peptide families from the skin secretions of the Chachi treefrog, Boana picturata. | J Proteomics | 2022