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Peptide record

TPDB19816

Antibacterial Anticancer Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB19816
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GGGGRGDRGDLPETGGS
Physicochemical Analysis
C59H97N23O26
ANCQHIKMFWYV
G
1544.56
4.31
2
3
1
-1
6.34
-1.294
22.94
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
2
D
0
C
1
E
0
Q
8
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 2 C: 0 E: 1 Q: 0 G: 8 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C59H97N23O26
1544.56
4.31
-1
6.34
-1.294
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
48.8 µM
Cytotoxic
IC50 | 48.8 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
New potent and selective αvβ3 integrin ligands: Macrocyclic peptides containing RGD motif synthesized by sortase A-mediated ligation. | Bioorg Med Chem Lett | 2017
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Bioorg Med Chem Lett. 2017 May 1 27(9):1911-1914