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Peptide record

TPDB19810

Antibacterial Antifungal standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB19810
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 28-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
GGDGSIAEYFNRPMHIHDWQIMDSGYYG
Physicochemical Analysis
C143H198N38O44S2
CLKTV
G
3217.49
4.42
3
4
11
-3
2.84
-0.714
45.36
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
9970
309.87
7
Residue Composition
number
1
A
1
R
1
N
3
D
0
C
1
E
1
Q
5
G
2
H
3
I
0
L
0
K
2
M
1
F
1
P
2
S
0
T
1
W
3
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 3 C: 0 E: 1 Q: 1 G: 5 H: 2 I: 3 L: 0 K: 0 M: 2 F: 1 P: 1 S: 2 T: 0 W: 1 Y: 3 V: 0
Chemical Descriptors
28
C143H198N38O44S2
3217.49
4.42
-3
2.84
-0.714
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µM

Target

B. cepacia ATCC 25416

Source & Reference

NA

Other

Active against B. cepacia ATCC 25416 (MIC 4 uM) and B. multivorans ATCC 17616 (MIC 31 uM), causative agents of lung infections in cystic
Evidence 2 Activity

Activity

MIC
Antibacterial
31 µM

Target

B. multivorans ATCC 17616

Source & Reference

NA

Other

Active against B. cepacia ATCC 25416 (MIC 4 uM) and B. multivorans ATCC 17616 (MIC 31 uM), causative agents of lung infections in cystic fibrosis patients. Spot on lawn active aga
Evidence 3 Activity

Activity

MIC
Antibacterial
0.25-0.5 µM

Target

B. cenocepacia AU0756

Source & Reference

NA

Other

active against also B. mallei Old ISU and B. mallei NVSL 86-567–562. Also active against B. cenocepacia AU0756 (MIC 0.25-0.5 uM) and B. cenocepacia AU24326 (MIC 2 uM) (Ref see SAR).
Evidence 4 Activity

Activity

MIC
Antibacterial
2 µM

Target

B. cenocepacia AU24326

Source & Reference

NA

Other

. mallei NVSL 86-567–562. Also active against B. cenocepacia AU0756 (MIC 0.25-0.5 uM) and B. cenocepacia AU24326 (MIC 2 uM) (Ref see SAR).
Evidence 5 Activity

Activity

MIC
Antifungal
4 µM

Target

B. cepacia ATCC 25416

Source & Reference

Antifungipept

Other

Active against B. cepacia ATCC 25416 (MIC 4 uM) and B. multivorans ATCC 17616 (MIC 31 uM), causative agents of lung infections in cystic
Evidence 6 Activity

Activity

MIC
Antifungal
31 µM

Target

B. multivorans ATCC 17616

Source & Reference

Antifungipept

Other

Active against B. cepacia ATCC 25416 (MIC 4 uM) and B. multivorans ATCC 17616 (MIC 31 uM), causative agents of lung infections in cystic fibrosis patients. Spot on lawn active aga
Evidence 7 Activity

Activity

MIC
Antifungal
0.25-0.5 µM

Target

B. cenocepacia AU0756

Source & Reference

Antifungipept

Other

active against also B. mallei Old ISU and B. mallei NVSL 86-567–562. Also active against B. cenocepacia AU0756 (MIC 0.25-0.5 uM) and B. cenocepacia AU24326 (MIC 2 uM) (Ref see SAR).
Evidence 8 Activity

Activity

MIC
Antifungal
2 µM

Target

B. cenocepacia AU24326

Source & Reference

Antifungipept

Other

. mallei NVSL 86-567–562. Also active against B. cenocepacia AU0756 (MIC 0.25-0.5 uM) and B. cenocepacia AU24326 (MIC 2 uM) (Ref see SAR).