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Peptide record

TPDB19787

Antibacterial Toxicity modified_plain modified
19 amino acids
Basic Information
3D PDB MODEL
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TPDB19787
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 19-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GFXXGKXXGFXXGKXKKKK
Physicochemical Analysis
C62H104N18O13
ARNDCEQHILMPSTWYV
K
1309.62
11.21
6
0
2
+6
3.72
-1.021
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
0
L
6
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 6 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C62H104N18O13
1309.62
11.21
+6
3.72
-1.021
Evidence Records 3 records
Evidence 1 Activity

Activity

33.4% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
33.4% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
NOVEL ANTI-MICROBIAL PEPTIDOMIMETIC COMPOUNDS AND METHODS TO CALCULATE ANTI-MICROBIAL ACTIVITY | PATENT US 2012/0197004 A1 | 2012
Evidence 2 Activity

Activity

14.3% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
14.3% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
NOVEL ANTI-MICROBIAL PEPTIDOMIMETIC COMPOUNDS AND METHODS TO CALCULATE ANTI-MICROBIAL ACTIVITY | PATENT US 2012/0197004 A1 | 2012
Evidence 3 Activity

Activity

14% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
14% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De novo design of selective antibiotic peptides by incorporation of unnatural amino acids. | J Med Chem | 2007