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Peptide record

TPDB19775

Antibacterial Antifungal Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB19775
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
GFXSILKKVXPKVXAHXK
Physicochemical Analysis
C74H126N20O16
RNDCEQMTWY
K
1551.94
11.00
5
0
6
+4
3.48
-0.017
81.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
1
L
4
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 1 K: 4 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
18
C74H126N20O16
1551.94
11.00
+4
3.48
-0.017
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
11 µM
Hemolytic Cytotoxic
50% Hemolysis | 11 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of hydrocarbon stapling on the properties of ?-helical antimicrobial peptides isolated from the venom of hymenoptera. | Amino Acids | 2012
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
50% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of hydrocarbon stapling on the properties of ?-helical antimicrobial peptides isolated from the venom of hymenoptera. | Amino Acids | 2012