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Peptide record

TPDB19761

Antibacterial Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB19761
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
GFNEIVQDIEDFLQNLV
Physicochemical Analysis
C90H137N21O30
ARCHKMPSTWY
NDEQILFV
1993.20
2.83
0
4
8
-4
4.65
0.129
125.88
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
0
A
0
R
2
N
2
D
0
C
2
E
2
Q
1
G
0
H
2
I
2
L
0
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 2 C: 0 E: 2 Q: 2 G: 1 H: 0 I: 2 L: 2 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
17
C90H137N21O30
1993.20
2.83
-4
4.65
0.129
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>25.1 µM
Cytotoxic
50% Cell death | >25.1 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.20086159]CEM-SS cells:TC50(cause 50% Cell death) >25.1 µM.

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2010 Mar 54(3):1343-6.