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Peptide record

TPDB19759

Antibacterial Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB19759
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 29-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GFMDTAKNVAKNVAVTLLYNLKCKITKAC
Physicochemical Analysis
C140H237N37O39S3
REQHPSW
K
3158.83
9.91
5
1
14
+4
2.63
0.279
97.59
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1615
51.13
9
Residue Composition
number
4
A
0
R
3
N
1
D
2
C
0
E
0
Q
1
G
0
H
1
I
3
L
5
K
1
M
1
F
0
P
0
S
3
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 4 R: 0 N: 3 D: 1 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 5 M: 1 F: 1 P: 0 S: 0 T: 3 W: 0 Y: 1 V: 3
Chemical Descriptors
29
C140H237N37O39S3
3158.83
9.91
+4
2.63
0.279
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 4 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 64-128 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. enteritidis

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 4 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 64-128 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
64-128 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 4 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 64-128 ug/ml).
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP