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Peptide record

TPDB19755

Antibacterial Antifungal Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB19755
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
GFLSXLKKXLGKXXAHXK
Physicochemical Analysis
C67H115N19O15
RNDCEQIMPTWYV
K
1426.77
11.00
5
0
5
+4
2.09
-0.244
70.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
3
L
4
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 3 K: 4 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C67H115N19O15
1426.77
11.00
+4
2.09
-0.244
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
29 µM
Hemolytic Cytotoxic
50% Hemolysis | 29 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effect of hydrocarbon stapling on the properties of ?-helical antimicrobial peptides isolated from the venom of hymenoptera. | Amino Acids | 2012