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Peptide record

TPDB19740

Antibacterial Antifungal Toxicity standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB19740
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept
standard
No
A 48-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
GFGCPLNQYQCNSHCKSIRCRAGYCDAATLWMRCTCTGCSGKVALFIT
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C221H346N66O64S9
E
C
5240.12
8.31
6
1
16
+4
1.10
0.104
55.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
8980
1.71
21
Residue Composition
number
4
A
3
R
2
N
1
D
8
C
0
E
2
Q
5
G
1
H
2
I
3
L
2
K
1
M
2
F
1
P
3
S
4
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 4 R: 3 N: 2 D: 1 C: 8 E: 0 Q: 2 G: 5 H: 1 I: 2 L: 3 K: 2 M: 1 F: 2 P: 1 S: 3 T: 4 W: 1 Y: 2 V: 1
Chemical Descriptors
48 reviewed residue count
C221H346N66O64S9 sequence-only estimate (linear, free termini)
5240.12 sequence-only estimate (linear, free termini)
8.31 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
1.10 sequence-only estimate (linear, free termini)
0.104 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against Gram bacterium A. hydrophila, Gram+ S. aureus.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against Gram bacterium A. hydrophila, Gram+ S. aureus.