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Peptide record

TPDB19735

Antibacterial Antifungal standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB19735
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse
standard
No
A 37-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and AFP-GFuse, with an available 3D structural model.
Sequence
GFGCNLITSNPYQCSNHCKSVGYRGGYCKLRTVCTCY
Physicochemical Analysis
C174H267N51O52S6
ADEMW
C
4097.70
8.56
5
0
10
+4
0.09
-0.243
47.30
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6335
154.60
20
Residue Composition
number
0
A
2
R
3
N
0
D
6
C
0
E
1
Q
5
G
1
H
1
I
2
L
2
K
0
M
1
F
1
P
3
S
3
T
0
W
4
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 3 D: 0 C: 6 E: 0 Q: 1 G: 5 H: 1 I: 1 L: 2 K: 2 M: 0 F: 1 P: 1 S: 3 T: 3 W: 0 Y: 4 V: 2
Chemical Descriptors
37
C174H267N51O52S6
4097.70
8.56
+4
0.09
-0.243
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1448 µg/mL

Target

P.aeruginosa

Source & Reference

NA

Other

ctiae APC1055, and C. difficile DPC6534 (0.76 uM). Also tested using MRSA (MIC 23 ug/ml), P.aeruginosa (MIC 1448 ug/ml) and C. albicans (MIC 23 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
23 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

C6534 (0.76 uM). Also tested using MRSA (MIC 23 ug/ml), P.aeruginosa (MIC 1448 ug/ml) and C. albicans (MIC 23 ug/ml).
Evidence 3 Activity

Activity

MIC
Antifungal
1448 µg/mL

Target

P.aeruginosa

Source & Reference

NA

Other

ctiae APC1055, and C. difficile DPC6534 (0.76 uM). Also tested using MRSA (MIC 23 ug/ml), P.aeruginosa (MIC 1448 ug/ml) and C. albicans (MIC 23 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
23 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

C6534 (0.76 uM). Also tested using MRSA (MIC 23 ug/ml), P.aeruginosa (MIC 1448 ug/ml) and C. albicans (MIC 23 ug/ml).