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Peptide record

TPDB19655

Antibacterial Antiviral Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB19655
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
GAKKGAKKGKKGAKKGAKGAGAKGAGAFKKKK
Physicochemical Analysis
C135H246N46O33
RNDCEQHILMPSTWYV
K
3041.73
11.62
14
0
9
+14
11.46
-1.281
25.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
8
A
0
R
0
N
0
D
0
C
0
E
0
Q
9
G
0
H
0
I
0
L
14
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 9 H: 0 I: 0 L: 0 K: 14 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
32
C135H246N46O33
3041.73
11.62
+14
11.46
-1.281
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
6.19 µM
Cytotoxic
50% Cytotoxicity | 6.19 | µM | target cell: Feline kidney epithelial CRFK cells

Target

Feline kidney epithelial CRFK cells

Source & Reference

NA
DBAASP
Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | J Virol | 2002
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.12208971]CrFK cell:TC50=6.19 µM.

Source & Reference

NA
DRAMP
J Virol. 2002 Oct 76(19):9952-61.